[Jotaku]

As of March 2021, 10 best anime games in Steam by the order of Top Sellers are:
Yu-Gi-Oh! Duel Links
Phantasy Star Online 2
Persona® 5 Strikers
HuniePop 2: Double Date
DRAGON BALL FighterZ
NARUTO SHIPPUDEN: Ultimate Ninja STORM 4
NARUTO TO BORUTO: SHINOBI STRIKER
Persona 4 Golden
Attack on Titan 2 - A.O.T.2 - 進撃の巨人２
MapleStory

* We excluded Final Fantasy XIV, Street Fighter V because they are NOT anime games but somehow in the list of anime games by Steam. Having one or two in-game races that look like anime character doesn't mean the entire game is anime game.

As of March 2021, 10 best anime games in Steam by the order of Top Rated by Gamers are:
Doki Doki Literature Club!
NEKOPARA Vol. 0 ~ 2
Persona 4 Golden
NARUTO SHIPPUDEN: Ultimate Ninja STORM 4
Muse Dash
HuniePop
Mirror
Danganronpa: Trigger Happy Havoc
VRChat
Danganronpa 2: Goodbye Despair

You can always check best anime games in Steam in this page.